Scope of Practice7 min read · Published 2026-10-29

Who Can Inject Botox in South Dakota? Nurses and Licenses

A patient guide to the Board of Nursing's statement on nurses and Botox, the physician and assistant boards, esthetician limits and official license checks, with primary sources checked October 29, 2026.

Two hands in blue nitrile gloves drawing liquid from an upturned Xeomin vial into a graduated syringe against a dark background
An illustrative photograph of a neurotoxin vial being drawn into a syringe. It was not taken at any practice named or regulated in this guide.Photo: The Search Sherpa (thesearchsherpa.com)

The short answer

The South Dakota Board of Nursing says an RN or LPN may inject botulinum toxin as part of a medically prescribed plan of care, after a provider's assessment and under a medical order or written protocol. Its statement is guidelines without the force of law, but it says state law does not let RNs or LPNs perform these procedures without an order or protocol. In the pages we reviewed, we found no license for med spas.

By Medical Spa Providers Editorial Team (Independent editorial research; primary references listed below)Updated 2026-10-29

Who regulates injectors in South Dakota


South Dakota does not have one agency for injectors. A person's license board depends on the license they hold, so the name on a med spa's door does not tell you which board to check. Start by asking for the full name and license type of the person who will treat you and the person who authorizes the treatment. Our guide to verifying credentials covers the general steps.

We found no South Dakota page that creates a license or registration category for medical spas or cosmetic injectors, and no Board of Medical and Osteopathic Examiners statement on cosmetic injections in the pages we reviewed. The Board of Nursing's statement is the main South Dakota document we found that names Botox.

BoardWho it covers in this guideWhere it fits
Board of Medical and Osteopathic ExaminersPhysicians (MD and DO) and physician assistantsLicenses them and receives complaints about them
Board of NursingRNs, LPNs and certified nurse practitionersLicenses nurses and issues the statement on dermatological procedures
Cosmetology CommissionEstheticians and cosmetologistsLicenses skin care that is noninvasive and not medical treatment

What the Board of Nursing says about RNs and LPNs


The Board of Nursing's statement, Dermatological Procedures by Licensed Nurses, says dermatologic and medical aesthetic services may be performed by a licensed RN or LPN as part of a medically prescribed plan of care. The page shows an initial approval date of 2002 and a most recent revision of November 2024. The board says its opinions do not have the force and effect of law but guide licensees toward safe practice. The same statement says South Dakota law does not allow an RN or LPN to perform these procedures without a medical order or protocol, and that nurses perform them according to agency policy.

The statement lists neuromodulators (botulinum toxin, such as Botox) among injectable treatments an RN may perform using FDA approved products, and lists injectable neuromodulator treatments among LPN procedures. It lists temporary dermal fillers for RNs but does not list them for LPNs. It also says an RN or LPN may not prescribe or perform these procedures without a medical order or protocol, even for elective services requested by a client in a non-traditional setting.

RoleWhat the nursing statement saysQuestion to ask the clinic
RNMay inject neuromodulators according to agency policy, with additional education, a provider assessment, a medical order or protocol and a nursing assessment.Who assessed me and wrote the order for this treatment?
LPNMay inject neuromodulators on the same conditions, according to agency policy, and must be supervised under South Dakota nursing law.Who supervises the LPN during my appointment?
Dermal fillersListed for RNs (temporary fillers). Not listed among LPN procedures.Is the person injecting filler an RN or a higher-level provider?

The medical provider, the order and the setting


The nursing statement expects an authorized medical provider (a physician, certified nurse practitioner or physician assistant acting within their South Dakota scope) to review the client's history, assess whether the procedure is appropriate for each episode of care, develop a treatment plan and write a medical order before delegating a procedure to a nurse. The assessment may be in person or by telehealth.

A protocol must be in writing, dated and signed by the medical provider and reviewed annually. It must set the nurse's required licensure level, experience and training, the level of supervision, when to consult the provider, and contraindications. The statement also expects the practice to keep client assessments, consent and procedure records, and to obtain substances from a South Dakota licensed wholesale drug distributor or licensed 503B outsourcing facility.

These are the board's expectations for nursing practice. Ask the clinic which provider assessed you, which order covers your treatment and where it is documented. Our guide to RN injector delegation explains why the order matters across states.

Physicians, physician assistants and lasers


The Board of Medical and Osteopathic Examiners licenses MD and DO physicians and physician assistants. Its physician assistant page quotes SDCL 36-4A-1.1, which describes a collaborative agreement signed by a physician assistant and a licensed physician. SDCL 36-4A-1.2, quoted on the same page, lets a physician assistant practice without one if the assistant is nationally certified and files an affidavit with the board attesting to at least 6,000 practice hours. The page does not mention Botox or cosmetic injections.

In the pages we reviewed, we found no Board of Medical and Osteopathic Examiners statement on cosmetic injections. The board has a March 28, 2012 declaratory ruling on laser delegation. As we captured it, the ruling states that lasers and light emitting devices are surgery and the practice of medicine, and that the board held physicians may not delegate laser procedures. It also says the Board of Nursing defines nurses' scope and the ruling does not affect nurses. Our capture of the ruling is incomplete, so read the full ruling. The Board of Nursing's statement separately reports that the Board of Medical and Osteopathic Examiners determined that only physicians, nurse practitioners and physician assistants may use lasers.

A laser treatment and a Botox injection raise different questions. Ask for the individual's license type and what authorizes the specific treatment you were offered.

Estheticians and the Cosmetology Commission


The Cosmetology Commission says it regulates skin care and esthetics and that in no case may the regulated procedures be invasive or medical treatments. Its scope document quotes SDCL 36-15-2.2, which limits esthetics to noninvasive care confined to the nonliving cells of the outer skin layer, not for treating medical disorders. The document is dated July 3, 2017, so check the commission for later changes.

The same document quotes SDCL 36-15-16, which says the cosmetology chapter does not apply to licensed physicians, physician assistants and nurses when exclusively engaged in their own professions. Combined with the limits above, an esthetician license alone is not a basis for injecting. Our esthetician scope guide goes further.

Does South Dakota register cosmetic injectors or med spas


We found no South Dakota license or registration for medical spas, and no state list of cosmetic injectors, on the board pages we reviewed. Practitioners hold the license for their own profession.

The nursing statement does require one registration. A CNP or RN who owns a business providing dermatologic or medical aesthetic services must register it with the Board of Nursing as a nursing corporation. That concerns the owner's board, not the patient's safety check.

How to verify a license and file a complaint


For a nurse, use the license verification portal that the Board of Nursing links from its home page. Search by name, license number or NCSBN ID, choose the license type (RN, LPN or an APRN type) and click View Report for the full details. For a physician or physician assistant, use the Board of Medical and Osteopathic Examiners' licensee lookup, which shows the profile and expiration date at no charge. For an esthetician or salon, use the Cosmetology Commission's license verification.

To report a nurse, use the Board of Nursing's complaint form. To report a physician or physician assistant, use the Board of Medical and Osteopathic Examiners' complaint form; the board says it has no jurisdiction over fees, registered nurses or most facilities. Cosmetology complaints go to the Commission in writing on its complaint form. See also our complaint guide.

Compare the name and license type you find with the person assigned to your appointment. A lookup confirms licensure status, and each board publishes public discipline separately. Neither shows whether a given order or protocol exists.

A license check is only part of the decision

A license lookup does not judge a clinician's technique or whether Botox is right for you. Ask about experience with your proposed treatment, the assessment that precedes it, the order that covers it, aftercare and who to contact afterward.

Frequently asked questions

Can a nurse inject Botox in South Dakota?

The Board of Nursing says an RN may inject neuromodulators such as Botox as part of a medically prescribed plan of care. The RN needs added education, a provider's assessment, and a medical order or written protocol. The board's statement lacks the force of law, but it says state law bars the procedure without an order or protocol.

Can an LPN inject Botox in South Dakota?

The Board of Nursing lists injectable neuromodulator treatments among LPN procedures, with the same education, assessment and order or protocol conditions as for an RN, plus supervision under South Dakota nursing rules. Ask the clinic who supervises the LPN during your appointment.

Does South Dakota license med spas?

We found no South Dakota license or registration category for medical spas or cosmetic injectors in the board pages we reviewed. Practitioners are licensed by their own boards, such as the Board of Nursing or the Board of Medical and Osteopathic Examiners. Check each named professional individually.

How do I check a South Dakota provider's license?

Use the board that licenses the person. The Board of Nursing has a verification portal for RNs, LPNs and APRNs. The Board of Medical and Osteopathic Examiners has a licensee lookup for physicians and physician assistants. The Cosmetology Commission verifies estheticians. Match the name and license type to your appointment.

Sources

Primary references behind this guide. Each link opens the publisher’s own page.

  1. Dermatological Procedures by Licensed Nurses (revised November 2024)South Dakota Board of Nursingaccessed 2026-10-29
  2. Verify Nurse: license verification (linked from the board home page; portal hosted by NCSBN)South Dakota Board of Nursingaccessed 2026-10-29
  3. Complaints and Disciplinary ProcessSouth Dakota Board of Nursingaccessed 2026-10-29
  4. Physician Assistant: collaborative agreementSouth Dakota Board of Medical and Osteopathic Examinersaccessed 2026-10-29
  5. Declaratory Ruling on lasers (March 28, 2012)South Dakota Board of Medical and Osteopathic Examinersaccessed 2026-10-29
  6. Licensee LookupSouth Dakota Board of Medical and Osteopathic Examinersaccessed 2026-10-29
  7. ComplaintsSouth Dakota Board of Medical and Osteopathic Examinersaccessed 2026-10-29
  8. South Dakota Cosmetology CommissionSouth Dakota Department of Labor and Regulationaccessed 2026-10-29
  9. Scope of Practice in South Dakota CosmetologySouth Dakota Cosmetology Commissionaccessed 2026-10-29
  10. Consumer ComplaintsSouth Dakota Cosmetology Commissionaccessed 2026-10-29

Before you book

Verify the injector first

Use the official lookups to confirm the names a clinic gives you, then ask about the order that covers your treatment.

See how to verify credentials

Educational information about licensing and patient questions, not medical or legal advice. Primary sources were checked October 29, 2026. Confirm current guidance with the relevant board for a specific arrangement.

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